25.04.2024 | Letter to the Editor
A case report illustrating the ‘hypotensive twilight zone’ in Parkinson’s disease; an under-recognised presentation of orthostatic hypotension
verfasst von:
J. Gert van Dijk, Bastiaan R. Bloem
Erschienen in:
Clinical Autonomic Research
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Excerpt
A 67-year-old woman with Parkinson’s disease (PD) was referred for almost daily episodes of reduced responsiveness. Most spells occurred during breakfast, 30 min after taking her first levodopa dose. Her husband noticed she slumped backwards in her chair, staying upright. She stared ahead and did not respond when prodded or spoken to. Such spells could last one hour. She would later remember parts of such periods. Spells also occurred when sitting on a stool while showering. When helped to lie down, the spells ended immediately. She had PD since the age of 60 and used a combination of levodopa/carbidopa and levodopa/benserazide with a net daily dose of 750 mg of levodopa. Her prior history included knee joint problems. Cognitive problems were absent then and later. …
