Ocular tuberculosis (TB) presents with a variety of intraocular clinical features like conjunctival granuloma, granulomatous anterior uveitis, multifocal choroiditis, chorioretinitis, choroidal granulomas and retinal vasculitis [
1,
2]. Periphlebitis is a common manifestation of TB uveitis and was known earlier as Eales’ disease. Tubercular retinal vasculitis initially presenting as the central or branch retinal vein or artery occlusions with or without other ocular signs of TB has been rarely described previously [
3‐
7]. Acute macular neuroretinopathy (AMN) was described by Bos and Deutman in 1975 as a characteristic red, wedge-shaped defect affecting the macular inner retinal layers [
8]. With the more sophisticated imaging systems, such as spectral-domain optical coherence tomography (SD-OCT), Sarraf et al. classified AMN into 2 types: (a) type 1 AMN, where hyperreflective band is noted in the outer plexiform layer/inner nuclear layer region with subsequent inner nuclear layer thinning and (b) type 2 AMN, where hyperreflective band is seen in the outer plexiform layer/outer nuclear layer region with subsequent outer nuclear layer thinning and concomitant defects of the inner segment/outer segment layer [
9]. Later, type 1 AMN came to be known as paracentral acute middle maculopathy and type 2 AMN as acute macular outer retinopathy. Patients with AMN complain of sudden blurring of vision with paracentral scotoma usually in the one eye. The diagnosis of AMN is confirmed by characteristic imaging features on SD-OCT. Analysis of risk factors in AMN seems to suggest a retinal microvascular aetiology [
10]. Ocular TB as a cause of AMN has not been described in the literature to the best of our knowledge. In this report, we describe a case of ocular TB presenting with combined central retinal vein occlusion and type 2 AMN and treated successfully with antitubercular therapy (ATT) and oral corticosteroids.