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Graefe's Archive for Clinical and Experimental Ophthalmology

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29.09.2023 | Inflammatory Disorders

Are optical coherence tomography and fluorescein angiography comparable for detection of macular edema in Behçet uveitis?

verfasst von: Mehmet Fatih Kağan Değirmenci, F. Nilüfer Yalçındağ

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 11/2023

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Abstract

Purpose

To investigate the role and agreement of spectral domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) for macular edema (ME) diagnosis in Behçet uveitis (BU).

Methods

Eyes with ME detected by SD-OCT and/or FA were enrolled. Type of ME by SD-OCT and grade of macular leakage (ML) by FA were investigated. Eyes were divided into three groups according to the agreement of tests. Three groups and factors that could affect the compatibility of tests were statistically analyzed.

Results

Sixty-one eyes of 61 patients were included. Both imaging methods detected ME in 42.6% of eyes (group 1). In 47.5% of eyes, ME was revealed by OCT (group 2). The remaining 9.8% of the eyes had ME, detected only by FA (group 3). Grade 2 ML by FA was more common in group 1 (p = 0.01). The grade of ML by FA was similar in groups 2 and 3. In group 2, most of the eyes showed diffuse ME by OCT (p < 0.001). Epiretinal membrane was detected more frequently in group 3 (p = 0.005). Duration and activity of uveitis were similar between groups.

Conclusion

SD-OCT was able to detect ME in 90% of the eyes with BU. Duration and activity of uveitis were not related to the compatibility of imaging methods.

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Titel: Are optical coherence tomography and fluorescein angiography comparable for detection of macular edema in Behçet uveitis?
verfasst von: Mehmet Fatih Kağan Değirmenci
F. Nilüfer Yalçındağ
Publikationsdatum: 29.09.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 11/2023
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-023-06249-0

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