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Indian Journal of Otolaryngology and Head & Neck Surgery

Erschienen in:

14.02.2023 | COVID-19 | Other Articles

Human Nasal Epithelium Damage as the Probable Mechanism Involved in the Development of Post-COVID-19 Parosmia

verfasst von: Xolalpa-Peniche Andrea, Lucas-Mata Joceline, Osante-Forastieri Jose, Pérez-Ochoa Jose

Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery | Sonderheft 1/2023

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Abstract

Purpose

Since the beginning of the COVID-19 pandemic, understanding the physiopathological mechanisms of its manifestations has been crucial to understand the disease and its implications. As the disease evolved, post-infection complications have arisen such as olfactory dysfunctions including parosmia in which odourants are perceived in a distorted or an unpleasant way.

Methods

In this article, we attempt to clarify these mechanisms and the role of human nasal epithelium in the development of post-COVID-19 parosmia.

Results

The mechanisms by which SARS-CoV-2 generates olfactory dysfunction have not been elucidated, and multiple theories have been proposed pointing to the sustentacular cells of the olfactory epithelium as the main probable target of the virus.

Conclusion

Establishing the main physiopathological mechanism of post-COVID-19 parosmia will set a path for further investigations and determine treatment and preventive options for patients who have been reported to be extensively affected in multiple aspects of their lives such as eating habits and mental health.

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Titel: Human Nasal Epithelium Damage as the Probable Mechanism Involved in the Development of Post-COVID-19 Parosmia
verfasst von: Xolalpa-Peniche Andrea
Lucas-Mata Joceline
Osante-Forastieri Jose
Pérez-Ochoa Jose
Publikationsdatum: 14.02.2023
Verlag: Springer India
Schlagwort: COVID-19
Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery / Ausgabe Sonderheft 1/2023
Print ISSN: 2231-3796
Elektronische ISSN: 0973-7707
DOI: https://doi.org/10.1007/s12070-023-03559-x

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Human Nasal Epithelium Damage as the Probable Mechanism Involved in the Development of Post-COVID-19 Parosmia

Abstract

Purpose

Methods

Results

Conclusion

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Abstract

Purpose

Methods

Results

Conclusion

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