Erschienen in:
21.01.2023 | EDITORIAL
Dormancy in cancer metastasis: keys to moving forward
verfasst von:
Danny R. Welch
Erschienen in:
Cancer and Metastasis Reviews
|
Ausgabe 1/2023
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Excerpt
If diagnosed prior to spread, surgical removal of cancer is curative. If metastases already exist at the time of diagnosis, prognosis drops dramatically, and quality-of-life is significantly diminished [
1]. It is cancers in patients with no evidence of metastases — but in whom the cancer cells have already disseminated and will recur later — that are the focus of this special issue of
Cancer and Metastasis Reviews. Recurrence of cancer is always devastating news. But when the cancer has lain dormant for months or years before resurrection, the psychological impact on cancer patients is doubly difficult. Likewise, during this silent phase of cancer, accumulations of additional mutations likely contribute to subsequent difficulties in controlling the disease [
2]. …