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Zeitschrift für Rheumatologie

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17.02.2022 | Originalien

Integrated comparison of the mRNAome in cartilage, synovium, and macrophages in osteoarthritis

verfasst von: Siming Gao, Hui Song

Erschienen in: Zeitschrift für Rheumatologie | Sonderheft 1/2024

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Abstract

The precise molecular mechanisms associated with osteoarthritis (OA), the most common musculoskeletal disorder, are poorly understood. There are currently no effective treatments to prevent the initiation and progression of the disease. In recent years, the development of mRNAome has made it possible to identify new mechanisms and therapeutic targets. However, the differentially expressed genes screened by different microarrays are not completely the same. In order to avoid this shortcoming, we integrate the different genes from different tissues and data sets, and select the commonly expressed genes for further studies.

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Titel: Integrated comparison of the mRNAome in cartilage, synovium, and macrophages in osteoarthritis
verfasst von: Siming Gao
Hui Song
Publikationsdatum: 17.02.2022
Verlag: Springer Medizin
Erschienen in: Zeitschrift für Rheumatologie / Ausgabe Sonderheft 1/2024
Print ISSN: 0340-1855
Elektronische ISSN: 1435-1250
DOI: https://doi.org/10.1007/s00393-022-01171-y

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