Traumatic brain injury (TBI) is a major cause of death and disability [ 1 ]. One quarter of patients with severe TBI die, and more than 60% of these deaths are influenced by the decision to withdraw life-sustaining therapies [ 2 ]. Clinicians and …
verfasst von:
Ayham Alkhachroum, Emilia Fló, Brian Manolovitz, Holly Cohan, Berje Shammassian, Danielle Bass, Gabriela Aklepi, Esther Monexe, Pardis Ghamasaee, Evie Sobczak, Daniel Samano, Ana Bolaños Saavedra, Nina Massad, Mohan Kottapally, Amedeo Merenda, Joacir Graciolli Cordeiro, Jonathan Jagid, Andres M. Kanner, Tatjana Rundek, Kristine O’Phelan, Jan Claassen, Jacobo D. Sitt
Despite improvements in survival after illnesses requiring extracorporeal life support, cerebral injury continues to hinder successful outcomes. Cerebral autoregulation (CA) is an innate protective mechanism that maintains constant cerebral blood …
verfasst von:
Nolan Chalifoux, Tiffany Ko, Julia Slovis, Audrey Spelde, Todd Kilbaugh, Constantine D. Mavroudis
Our understanding of intracranial pressure (ICP), a critical indicator of brain health, is continuously evolving [ 1 ], with satisfactory evidence supporting its monitoring as a means of outcome improvement [ 2 , 3 ]. However, both the safety …
verfasst von:
Sérgio Brasil, Daniel Agustín Godoy, Walter Videtta, Andrés Mariano Rubiano, Davi Solla, Fabio Silvio Taccone, Chiara Robba, Frank Rasulo, Marcel Aries, Peter Smielewski, Geert Meyfroidt, Denise Battaglini, Mohammad I. Hirzallah, Robson Amorim, Gisele Sampaio, Fabiano Moulin, Cristian Deana, Edoardo Picetti, Angelos Kolias, Peter Hutchinson, Gregory W. Hawryluk, Marek Czosnyka, Ronney B. Panerai, Lori A. Shutter, Soojin Park, Carla Rynkowski, Jorge Paranhos, Thiago H. S. Silva, Luiz M. S. Malbouisson, Wellingson S. Paiva
New hemato-oncologic treatment regimens, such as CAR-T cell therapy, require patients to stay in intensive care units. Neurointensivists are increasingly involved in evaluating neurologic complications, and for a good reason. The increasing …
verfasst von:
Eelco F. M. Wijdicks, Alejandro A. Rabinstein, Yi Lin
Nearly all health care professionals use smartphone devices, and there is an increasing number of smartphone applications that are geared toward the medical field. Despite this, relatively little is known about how health professionals use …
verfasst von:
Melissa B. Pergakis, Afrah A. Ali, WanTsu Wendy Chang, Benjamin Neustein, Casey Albin, Aimee Aysenne, Samuel A. Tisherman, Nicholas A. Morris
Severe traumatic brain injury (sTBI) (i.e., Glasgow Coma Scale [GCS] of ≤ 8) is a condition that includes focal contusions, intradural and extradural hematomas, and diffuse axonal injuries [ 1 ]. These injuries often lead to severe lifelong …
verfasst von:
Emma Andersson, Martin Öst, Keti Dalla, Henrik Zetterberg, Kaj Blennow, Bengt Nellgård
Epilepsy is characterized by recurrent unprovoked seizures and is one of the world’s oldest recognized medical conditions. Currently, approximately 50 million people worldwide are diagnosed with epilepsy [ 1 ]. Most seizures are brief and …
verfasst von:
Marjorie Jia Yi Ong, Vanessa Lin Lin Lee, Sze Lynn Teo, Hui Jan Tan, Eugen Trinka, Ching Soong Khoo
Traumatic brain injury (TBI) remains a public health problem, often resulting in long-term neurological complications [ 1 , 2 ]. Neuroinflammation, characterized by the activation of astrocytes and microglia leading to the release of tumor necrosis …
verfasst von:
Tee-Tau Eric Nyam, Hsiao-Yue Wee, Min-Hsi Chiu, Kuan-Chi Tu, Che-Chuan Wang, Yao-Tsung Yeh, Ching-Lung Kuo
Public trust in brain death or death by neurological criteria (DNC) is imperative, particularly in the context of organ donation [ 1 ]. To ensure that organ donation adheres to the Dead Donor Rule [ 2 ] (which requires death before donation), the …
verfasst von:
Kasra Sarhadi, Kristopher A. Hendershot, Natalie Smith, Michael Souter, Claire Creutzfeldt, Abhijit Lele, Carolina Maciel, Katharina Busl, Julius Balogh, David Greer, Ariane Lewis, Sarah Wahlster
Hemorrhagic strokes account for approximately 10–15% of all strokes but have mortality rates as high as 50% [ 1 ]. Hemorrhagic transformation of ischemic strokes, a feared complication that leads to poor outcomes, occurs at a rate of nearly 40% [ 2 …]. Spontaneous intracerebral hemorrhage (sICH) has the highest mortality of all stroke subtypes, and of those patients who survive, most do not regain functional independence [
verfasst von:
Bao Y. Sciscent, David R. Hallan, Debarati Bhanja, Jacob Staub, Derek Crossman, Elias B. Rizk, J. Christopher Zacko, Haejoe Park, Sprague W. Hazard
Traumatic brain injury (TBI) accounts for a substantial global health burden, with approximately 27 million cases reported annually, particularly in low-income and middle-income countries [ 1 , 2 ]. As many as 50% of individuals with TBI do not …
verfasst von:
Eder Cáceres, Afshin A. Divani, Clio A. Rubinos, Juan Olivella-Gómez, André Emilio Viñan Garcés, Angélica González, Alexis Alvarado Arias, Kunal Bhatia, Uzma Samadani, Luis F. Reyes
Subarachnoid hemorrhage (SAH) remains a significant cause of global morbidity and mortality. Mortality in these patients is reportedly ~ 25%, and roughly 50% of survivors are left with some persistent neurological deficit [ 1 ]. There are estimates …
verfasst von:
Chidozie Ukpabi, Ofer Sadan, Yuyang Shi, Kristy N. Greene, Owen Samuels, Subin Mathew, Justin Joy, Yajun Mei, William Asbury
Ischemia is defined as insufficient oxygen supply to tissues and being unable to meet their demands and involves the cessation of oxygenated blood flow, leading to hypoxia [ 1 , 2 ]. The human brain is particularly vulnerable to hypoxic conditions …
verfasst von:
Dimitris Moustakas, Iliana Mani, Abraham Pouliakis, Nikoletta Iacovidou, Theodoros Xanthos
30.04.2024 | Pediatric Neurocritical Care and Neuromonitoring
Cardiac arrest survival rates are steadily improving [ 1 ]. However, after medical stabilization and hospital discharge, survivors rarely receive appropriate follow-up care to manage their cognitive, physical, and emotional challenges resulting …
verfasst von:
Alexander M. Presciutti, Sarah M. Perman, Ana-Maria Vranceanu
The ictal–interictal continuum (IIC) is commonly seen in adults with critical neurologic injury [ 1 , 2 ]. It consists of rhythmic and periodic patterns (RPP) that do not clearly qualify as an electrographic seizure (ES) or electrographic status …
verfasst von:
Arnold J. Sansevere, Julia S. Keenan, Elizabeth Pickup, Caroline Conley, Katelyn Staso, Dana B. Harrar
The study “Coma Prevalence in Critical Care Units in Chile”, conducted on World Coma Day, is a pivotal contribution to understanding coma epidemiology in South American health care settings [ 1 ]. The article provides valuable data on coma …
