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Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery 2/2023

17.11.2022 | Original Article

KTP 532 Laser Assisted Surgery for Oral Cavity Malignancy—A Retrospective Study

verfasst von: Dipak Ranjan Nayak, R. Balakrishnan, Pooja Dalakoti, Uday Bhanu, Suraj Nair, Kailesh Poojary

Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery | Ausgabe 2/2023

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Abstract

Aims and Objective

To determine the effectiveness of KTP 532 in surgically treating early and early advanced oral malignancy with no surgical reconstruction of primary site.

Materials and methods

It is a retrospective study of 67 cases operated between 2000 to 2013 including T1, T2 and Early T3 cases, approved by ethical committee. All the cases underwent Laser assisted excision of tumour with or without Neck Dissection or Adjuvant Radiotherapy. Age of the cases varied from 20 to 80 years with mean age of 49 years. 47 cases were males and 20 were females. 26 cases in the study had neck nodes clinically whereas 41 cases had N0 status. Neck dissection was done (SOND or MRND) in 61 cases. In 6 cases (N0) no neck dissection was done.

Results

61 cases had no loco-regional residual disease on their last follow up. Six cases had loco-regional recurrence within 6 months and salvage surgery was done. The overall mean survival was 81 months (92, 82 and 71 months in Stage I, II,III respectively). 3 year disease free survival rate was 91% as calculated using Kaplan- Meier Scale. In all these cases tumour was excised with KTP 532 laser and no reconstruction was done. Wound was allowed to heal with secondary intention.

Conclusion

Laser assisted excision of oral malignancy is an alternative to conventional treatment with more precision, less morbidity, shorter hospital stay and better functional outcomes.
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Literatur
1.
2.
Zurück zum Zitat Fornain C, Rocca JP, Merigo E, Meleti M, Manfredi M, Nammour S, Vescovi P (2012 Mar) Low energy KTP laser in oral soft tissues surgery: a 52 patients clinical study. Medicina oral, patologia oral y cirugia bucal. 17:e2872 Fornain C, Rocca JP, Merigo E, Meleti M, Manfredi M, Nammour S, Vescovi P (2012 Mar) Low energy KTP laser in oral soft tissues surgery: a 52 patients clinical study. Medicina oral, patologia oral y cirugia bucal. 17:e2872
3.
Zurück zum Zitat Gaspar L (1994) The use of high-power lasers in oral surgery. J Clin Laser Med Surg 12(5):281–285CrossRefPubMed Gaspar L (1994) The use of high-power lasers in oral surgery. J Clin Laser Med Surg 12(5):281–285CrossRefPubMed
4.
Zurück zum Zitat Neukam FW, Stelzle F (2010 Jan) Laser tumor treatment in oral and maxillofacial surgery. Physics Procedia 1:5:91–100 Neukam FW, Stelzle F (2010 Jan) Laser tumor treatment in oral and maxillofacial surgery. Physics Procedia 1:5:91–100
5.
Zurück zum Zitat Strauss RA, Fallon SD (2004) Lasers in contemporary oral and maxillofacial surgery. Dent Clin North Am 48(4):861–888CrossRefPubMed Strauss RA, Fallon SD (2004) Lasers in contemporary oral and maxillofacial surgery. Dent Clin North Am 48(4):861–888CrossRefPubMed
6.
Zurück zum Zitat Ishii J et al (2001) Clinical assessment of KTP laser surgery for tongue lesions—Comparison with CO 2 laser surgery. J Jpn Soc Laser Dentistry 12:10–15CrossRef Ishii J et al (2001) Clinical assessment of KTP laser surgery for tongue lesions—Comparison with CO 2 laser surgery. J Jpn Soc Laser Dentistry 12:10–15CrossRef
7.
Zurück zum Zitat Lim B, Smith A, Chandu A Treatment of Oral Leukoplakia With Carbon Dioxide and Potassium-Titanyl-Phosphate Lasers: A Comparison.Journal of Oral and Maxillofacial Surgery. 68(3): p.597–601 Lim B, Smith A, Chandu A Treatment of Oral Leukoplakia With Carbon Dioxide and Potassium-Titanyl-Phosphate Lasers: A Comparison.Journal of Oral and Maxillofacial Surgery. 68(3): p.597–601
8.
Zurück zum Zitat Basu MK, Frame JW, Rhys PH, Evans (1988) Wound healing following partial glossectomy using the CO 2 laser, diathermy and scalpel: a histological study in rats. J laryngology otology 102(4):322–327CrossRef Basu MK, Frame JW, Rhys PH, Evans (1988) Wound healing following partial glossectomy using the CO 2 laser, diathermy and scalpel: a histological study in rats. J laryngology otology 102(4):322–327CrossRef
9.
Zurück zum Zitat Lippert BM et al (2003) Wound healing after laser treatment of oral and oropharyngeal cancer. Lasers Med Sci 18(1):36–42CrossRefPubMed Lippert BM et al (2003) Wound healing after laser treatment of oral and oropharyngeal cancer. Lasers Med Sci 18(1):36–42CrossRefPubMed
10.
Zurück zum Zitat Singh GB, Tiwari M, Shukla HS, Pandey M (2009) Nd:YAG laser therapy of carcinoma lip (stage I squamous cell carcinoma): a retrospective evaluation. Indian J Otolaryngol Head Neck Surg 61(3):179–184CrossRefPubMedPubMedCentral Singh GB, Tiwari M, Shukla HS, Pandey M (2009) Nd:YAG laser therapy of carcinoma lip (stage I squamous cell carcinoma): a retrospective evaluation. Indian J Otolaryngol Head Neck Surg 61(3):179–184CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Ihler C, Martin F, Wolff A, Matthias HA, Steiner C (2013) Enoral laser microsurgery for squamous cell carcinoma of the oral cavity. Head Neck 25(10):23365 Ihler C, Martin F, Wolff A, Matthias HA, Steiner C (2013) Enoral laser microsurgery for squamous cell carcinoma of the oral cavity. Head Neck 25(10):23365
12.
Zurück zum Zitat Ishii J, Fujita K, Komori T (2002) Clinical assessment of laser monotherapy for squamous cell carcinoma of the mobile tongue. J Clin Laser Med Surg 20(2):57–61CrossRefPubMed Ishii J, Fujita K, Komori T (2002) Clinical assessment of laser monotherapy for squamous cell carcinoma of the mobile tongue. J Clin Laser Med Surg 20(2):57–61CrossRefPubMed
13.
Zurück zum Zitat Carew JF, Ward RF, LaBruna A, Torzilli PA, Schley WS (1998) Effects of scalpel, electrocautery, and CO2 and KTP lasers on wound healing in rat tongues. The Laryngoscope. Mar 1;108(3):373 – 80 Carew JF, Ward RF, LaBruna A, Torzilli PA, Schley WS (1998) Effects of scalpel, electrocautery, and CO2 and KTP lasers on wound healing in rat tongues. The Laryngoscope. Mar 1;108(3):373 – 80
14.
Zurück zum Zitat Kaya G, Yavuz GY, Sümbüllü MA, Dayı E (2012) A comparison of diode laser and Er: YAG lasers in the treatment of gingival melanin pigmentation. Oral surgery, oral medicine, oral pathology and oral radiology. Mar 1;113(3):293-9 Kaya G, Yavuz GY, Sümbüllü MA, Dayı E (2012) A comparison of diode laser and Er: YAG lasers in the treatment of gingival melanin pigmentation. Oral surgery, oral medicine, oral pathology and oral radiology. Mar 1;113(3):293-9
15.
Zurück zum Zitat Kawczyk-Krupka A, Waśkowska J, Raczkowska-Siostrzonek A, Kościarz-Grzesiok A, Kwiatek S, Straszak D, Latos W, Koszowski R, Sieroń A (2012) Comparison of cryotherapy and photodynamic therapy in treatment of oral leukoplakia. Photodiagnosis and photodynamic therapy. Jun 1;9(2):148 – 55 Kawczyk-Krupka A, Waśkowska J, Raczkowska-Siostrzonek A, Kościarz-Grzesiok A, Kwiatek S, Straszak D, Latos W, Koszowski R, Sieroń A (2012) Comparison of cryotherapy and photodynamic therapy in treatment of oral leukoplakia. Photodiagnosis and photodynamic therapy. Jun 1;9(2):148 – 55
16.
Zurück zum Zitat Montebugnoli L, Frini F, Gissi DB, Gabusi A, Cervellati F, Foschini MP, Marchetti C (2012 Jan) Histological and immunohistochemical evaluation of new epithelium after removal of oral leukoplakia with Nd: YAG laser treatment. Lasers in medical science. 27:205–2101 Montebugnoli L, Frini F, Gissi DB, Gabusi A, Cervellati F, Foschini MP, Marchetti C (2012 Jan) Histological and immunohistochemical evaluation of new epithelium after removal of oral leukoplakia with Nd: YAG laser treatment. Lasers in medical science. 27:205–2101
17.
Zurück zum Zitat Hegde R, Padhye A, Sumanth S, Jain AS, Thukral N (2013 Jun) Comparison of surgical stripping; erbium-doped: yttrium, aluminum, and garnet laser; and carbon dioxide laser techniques for gingival depigmentation: a clinical and histologic study. J Periodontol 84(6):738–748 Hegde R, Padhye A, Sumanth S, Jain AS, Thukral N (2013 Jun) Comparison of surgical stripping; erbium-doped: yttrium, aluminum, and garnet laser; and carbon dioxide laser techniques for gingival depigmentation: a clinical and histologic study. J Periodontol 84(6):738–748
18.
Zurück zum Zitat Vescovi P, Manfredi M, Merigo E, Meleti M, Fornaini C, Rocca JP, Nammour S (2010) Surgical approach with Er: YAG laser on osteonecrosis of the jaws (ONJ) in patients under bisphosphonate therapy (BPT). Lasers in medical science. Jan;25(1):101 – 13 Vescovi P, Manfredi M, Merigo E, Meleti M, Fornaini C, Rocca JP, Nammour S (2010) Surgical approach with Er: YAG laser on osteonecrosis of the jaws (ONJ) in patients under bisphosphonate therapy (BPT). Lasers in medical science. Jan;25(1):101 – 13
19.
Zurück zum Zitat Misra N, Chittoria N, Umapathy D, Misra P (2013 Mar) Efficacy of diode laser in the management of oral lichen planus. Case Rep 15:2013:bcr2012007609 Misra N, Chittoria N, Umapathy D, Misra P (2013 Mar) Efficacy of diode laser in the management of oral lichen planus. Case Rep 15:2013:bcr2012007609
20.
Zurück zum Zitat Fornaini C, Raybaud H, Augros C, Rocca JP New clinical approach for use of Er: YAG laser in the surgical treatment of oral lichen planus: a report of two cases. Photomedicine and laser surgery. 2012 Apr 1;30(4):234-8 Fornaini C, Raybaud H, Augros C, Rocca JP New clinical approach for use of Er: YAG laser in the surgical treatment of oral lichen planus: a report of two cases. Photomedicine and laser surgery. 2012 Apr 1;30(4):234-8
21.
Zurück zum Zitat Shafirstein G, Friedman A, Siegel E, Moreno M, Bäumler W, Fan CY, Morehead K, Vural E, Stack BC, Suen JY (2011) Using 5-aminolevulinic acid and pulsed dye laser for photodynamic treatment of oral leukoplakia. Archives of Otolaryngology–Head & Neck Surgery. Nov 1;137(11):1117-23 Shafirstein G, Friedman A, Siegel E, Moreno M, Bäumler W, Fan CY, Morehead K, Vural E, Stack BC, Suen JY (2011) Using 5-aminolevulinic acid and pulsed dye laser for photodynamic treatment of oral leukoplakia. Archives of Otolaryngology–Head & Neck Surgery. Nov 1;137(11):1117-23
22.
Zurück zum Zitat Akbulut N, Kursun ES, Tumer MK, Kamburoglu K, Gulsen U (2013 Apr) Is the 810-nm diode laser the best choice in oral soft tissue therapy? Eur J dentistry 7(02):207–211 Akbulut N, Kursun ES, Tumer MK, Kamburoglu K, Gulsen U (2013 Apr) Is the 810-nm diode laser the best choice in oral soft tissue therapy? Eur J dentistry 7(02):207–211
23.
Zurück zum Zitat Boj JR, Poirier C, Espasa E, Hernandez M, Espanya A (2009 May) Lower lip mucocele treated with an erbium laser. Pediatr Dent 15(3):249–252 Boj JR, Poirier C, Espasa E, Hernandez M, Espanya A (2009 May) Lower lip mucocele treated with an erbium laser. Pediatr Dent 15(3):249–252
24.
Zurück zum Zitat Asnaashari M, Mehdipour M, MoradiAbbasabadi F, Azari-Marhabi S (2015) Expedited removal of pyogenic granuloma by diode laser in a pediatric patient. J lasers Med Sci 6(1):40PubMedPubMedCentral Asnaashari M, Mehdipour M, MoradiAbbasabadi F, Azari-Marhabi S (2015) Expedited removal of pyogenic granuloma by diode laser in a pediatric patient. J lasers Med Sci 6(1):40PubMedPubMedCentral
25.
Zurück zum Zitat López-Jornet P, Camacho-Alonso F (2013 Jan) Comparison of pain and swelling after removal of oral leukoplakia with CO2 laser and cold knife: a randomized clinical trial. Medicina oral, patologia oral y cirugia bucal. 18:e381 López-Jornet P, Camacho-Alonso F (2013 Jan) Comparison of pain and swelling after removal of oral leukoplakia with CO2 laser and cold knife: a randomized clinical trial. Medicina oral, patologia oral y cirugia bucal. 18:e381
26.
Zurück zum Zitat Agha-Hosseini F, Moslemi E, Mirzaii-Dizgah I (2012) Comparative evaluation of low-level laser and CO2 laser in treatment of patients with oral lichen planus. International journal of oral and maxillofacial surgery. Oct 1;41(10):1265-9 Agha-Hosseini F, Moslemi E, Mirzaii-Dizgah I (2012) Comparative evaluation of low-level laser and CO2 laser in treatment of patients with oral lichen planus. International journal of oral and maxillofacial surgery. Oct 1;41(10):1265-9
27.
Zurück zum Zitat Jerjes W, Upile T, Hamdoon Z, Al-Khawalde M, Morcos M, Mosse CA, Hopper C (2012 Jan) CO2 laser of oral dysplasia: clinicopathological features of recurrence and malignant transformation. Lasers Med Sci 27(1):169–179 Jerjes W, Upile T, Hamdoon Z, Al-Khawalde M, Morcos M, Mosse CA, Hopper C (2012 Jan) CO2 laser of oral dysplasia: clinicopathological features of recurrence and malignant transformation. Lasers Med Sci 27(1):169–179
28.
Zurück zum Zitat Deppe H, Mücke T, Hohlweg-Majert B, Hauck W, Wagenpfeil S, Hölzle F (2012 Jan) Different CO2 laser vaporization protocols for the therapy of oral precancerous lesions and precancerous conditions: a 10-year follow-up. Lasers Med Sci 27(1):59–63 Deppe H, Mücke T, Hohlweg-Majert B, Hauck W, Wagenpfeil S, Hölzle F (2012 Jan) Different CO2 laser vaporization protocols for the therapy of oral precancerous lesions and precancerous conditions: a 10-year follow-up. Lasers Med Sci 27(1):59–63
29.
Zurück zum Zitat Yang SW, Tsai CN, Lee YS, Chen TA (2011) Treatment outcome of dysplastic oral leukoplakia with carbon dioxide laser—emphasis on the factors affecting recurrence. Journal of Oral and Maxillofacial Surgery. Jun 1;69(6):e78-87 Yang SW, Tsai CN, Lee YS, Chen TA (2011) Treatment outcome of dysplastic oral leukoplakia with carbon dioxide laser—emphasis on the factors affecting recurrence. Journal of Oral and Maxillofacial Surgery. Jun 1;69(6):e78-87
30.
Zurück zum Zitat Mozafari H, Farhadzadeh K, Rezaei F (2015) A study of the effects of CO2 laser therapy on oral lichen planus (OLP). J Appl Environ Biol Sci 5(9S):114–118 Mozafari H, Farhadzadeh K, Rezaei F (2015) A study of the effects of CO2 laser therapy on oral lichen planus (OLP). J Appl Environ Biol Sci 5(9S):114–118
31.
Zurück zum Zitat Yagüe García J, España Tost AJ, Berini Aytés L, Gay Escoda C (2009) Treatment of oral mucocele-scalpel versus CO2 laser. Medicina Oral, Patología Oral y Cirugia Bucal, vol. 14, num. 9, p. 469–474. 2009 Sep 1 Yagüe García J, España Tost AJ, Berini Aytés L, Gay Escoda C (2009) Treatment of oral mucocele-scalpel versus CO2 laser. Medicina Oral, Patología Oral y Cirugia Bucal, vol. 14, num. 9, p. 469–474. 2009 Sep 1
32.
Zurück zum Zitat Monteiro LS, Mouzinho J, Azevedo A, Câmara MI, Martins MA, La Fuente JM (2012) Treatment of epulis fissuratum with carbon dioxide laser in a patient with antithrombotic medication. Braz Dent J 23:77–81CrossRefPubMed Monteiro LS, Mouzinho J, Azevedo A, Câmara MI, Martins MA, La Fuente JM (2012) Treatment of epulis fissuratum with carbon dioxide laser in a patient with antithrombotic medication. Braz Dent J 23:77–81CrossRefPubMed
33.
Zurück zum Zitat Lindenmüller IH, Noll P, Mameghani T, Walter C (2010 Aug) CO2 laser-assisted treatment of a giant pyogenic granuloma of the gingiva. Int J Dent hygiene 8(3):249–252 Lindenmüller IH, Noll P, Mameghani T, Walter C (2010 Aug) CO2 laser-assisted treatment of a giant pyogenic granuloma of the gingiva. Int J Dent hygiene 8(3):249–252
34.
Zurück zum Zitat Işeri U, Özçakır-Tomruk C, Gürsoy-Mert H (2009) Treatment of epulis fissuratum with CO2 laser and prosthetic rehabilitation in patients with vesiculobullous disease. Photomedicine and Laser Surgery. Aug 1;27(4):675 – 81 Işeri U, Özçakır-Tomruk C, Gürsoy-Mert H (2009) Treatment of epulis fissuratum with CO2 laser and prosthetic rehabilitation in patients with vesiculobullous disease. Photomedicine and Laser Surgery. Aug 1;27(4):675 – 81
35.
Zurück zum Zitat Lai JB, Poon CY (2009) Treatment of ranula using carbon dioxide laser–Case series report. International journal of oral and maxillofacial surgery. Oct 1;38(10):1107-11 Lai JB, Poon CY (2009) Treatment of ranula using carbon dioxide laser–Case series report. International journal of oral and maxillofacial surgery. Oct 1;38(10):1107-11
Metadaten
Titel
KTP 532 Laser Assisted Surgery for Oral Cavity Malignancy—A Retrospective Study
verfasst von
Dipak Ranjan Nayak
R. Balakrishnan
Pooja Dalakoti
Uday Bhanu
Suraj Nair
Kailesh Poojary
Publikationsdatum
17.11.2022
Verlag
Springer India
Erschienen in
Indian Journal of Otolaryngology and Head & Neck Surgery / Ausgabe 2/2023
Print ISSN: 2231-3796
Elektronische ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-022-03214-x

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