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Lasers in Medical Science

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01.12.2023 | Original Article

NIR laser-conjugated glutathione-coated Mn-doped CuS nanoprisms as photothermal agent for cancer treatment

verfasst von: Mustafa M. Muhsen, Selma M. H. Al-Jawad, Ali A. Taha

Erschienen in: Lasers in Medical Science | Ausgabe 1/2023

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Abstract

The cancer treatment by laser-conjugated nanomaterial has become a new developing trend due of their unique physicochemical performance. The previous few studies reported the preparation of undoped CuS nanoprisms. The current research was concerned with the Mn doping effect on the CuS nanoprisms and its activity in tumor toxicity of M.D. Anderson-Metastatic Breast 231 (MDA-MB-231) cell line with laser treatment. To prepare a novel CuS and Mn-doped CuS nanoprisms with high surface area by two-phase colloidal method, copper nitrate and sulfur powder were used as sources of copper and sulfur respectively. The prepared nanoprisms were investigated as antibacterial and photothermal agents in MDA-MB-231 cancer treatment using near-infrared (NIR) laser. The Mn-CuS nanoprisms were modified with glutathione (GSH) to decrease the cytotoxicity and increase the biocompatibility. The characterization of synthesized nanoprisms involved the structural, compositional, surface charges, optical, and morphological property analyses. X-ray diffraction (XRD) showed the peaks of hexagonal covellite copper sulfide nanoparticles and additional diffraction peaks at Mn-CuS which are assigned to orthorhombic chalcocite CuS. The transmission electron microscopy (TEM) images showed that the CuS and Mn-CuS nanoparticles have nanoprism morphology. The antibacterial activity test revealed that the activity enhances by doping and the prepared Mn-CuS nanostructures were more effective against the Staphylococcus aureus and Escherichia coli bacteria. The results of photothermal treatment indicated that the cancer cells were effectively killed and the GSH@Mn-CuS nanoprisms are able to be used as an efficient theranostic agent for tumor photothermal therapy in the future.

Sreelekha N, Subramanyam K, Reddy DA, Murali G, Ramu S, Varma KR, Vijayalakshmi RP (2016) Structural, optical, magnetic and photocatalytic properties of Co doped CuS diluted magnetic semiconductor nanoparticles. Appl Surf Sci 378:330–340

Chaki SH, Tailor JP, Deshpande MP (2014) Synthesis and characterizations of undoped and Mn doped CuS nanoparticles. Adv Sci Lett 20:959–965

Xu C, Zhang Z, Ye Q, Liu X (2003) Nano electronic devices based on nanowire nanoworks. Chem Lett 32:198

Hsu SW, Ngo C, Bryks W, Tao AR (2015) Shape focusing during the anisotropic growth of CuS triangular nanoprisms. Chem Mater 27:4957–4963

Millstone JE, Wei W, Jones MR, Yoo H, Mirkin CA (2008) Iodide ions control seed-mediated growth of anisotropic gold nanoparticles. Nano Lett 8:2526–2529PubMedPubMedCentral

Ha TH, Koo HJ, Chung BH (2007) Shape-controlled syntheses of gold nanoprisms and nanorods influenced by specific adsorption of halide ions. J Phys Chem C 111:1123–1130

Métraux GS, Mirkin CA (2005) Rapid thermal synthesis of silver nanoprisms with chemically tailorable thickness. Adv Mater 17:412–415

Zhao R, Sun X, Sun J, Wang L, Han J (2017) Polypyrrole-modified CuS nanoprisms for efficient near-infrared photothermal therapy. RSC Adv 7:10143–10149

Wang ZH, Geng DY, Zhang YJ, Zhang ZD (2010) CuS: Ni flowerlike morphologies synthesized by the solvothermal route. Mater Chem Phys 122:241–245

10.

Yildirim MA, Ateş A, Astam A (2009) Annealing and light effect on structural, optical and electrical properties of CuS, CuZnS and ZnS thin films grown by the SILAR method. Phys E: Low-Dimens Syst Nanostructures 41:1365–1372

11.

Pei LZ, Wang JF, Tao XX, Wang SB, Dong YP, Fan CG, Zhang QF (2011) Synthesis of CuS and Cu1. 1Fe1. 1S2 crystals and their electrochemical properties. Mater Charact 62:354–359

12.

AL-Barram LF, AL-Jawad SM, Taha AA, Imran NJ (2020) Photothermal therapy of cancer cells enhanced by glutathione (GSH) modified small-sized gold nanoparticles. J Electromagn Waves Appl 34:2467–2487

13.

Pal M, Pal U, Jiménez JMGY, Pérez-Rodríguez F (2012) Effects of crystallization and dopant concentration on the emission behavior of TiO 2: Eu nanophosphors. Nanoscale Res Lett 7:1–12PubMedPubMedCentral

14.

Al-Jawad SM, Taha AA, Redha AM, Imran NJ (2021) Influence of nickel doping concentration on the characteristics of nanostructure CuS prepared by hydrothermal method for antibacterial activity. Surf Rev Lett 28:2050031

15.

Kundu J, Pradhan D (2013) Influence of precursor concentration, surfactant and temperature on the hydrothermal synthesis of CuS: structural, thermal and optical properties. New J Chem 37:1470–1478

16.

Poulose AC, Veeranarayanan S, Mohamed MS, Nagaoka Y, Aburto RR, Mitcham T et al (2015) Multi-stimuli responsive Cu₂S nanocrystals as trimodal imaging and synergistic chemo-photothermal therapy agents. Nanoscale 7:8378–8388PubMedPubMedCentral

17.

Deng X, Li K, Cai X, Liu B, Wei Y, Deng K et al (2017) A hollow-structured CuS@ Cu2S@ Au nanohybrid: synergistically enhanced photothermal efficiency and photoswitchable targeting effect for cancer theranostics. Adv Mater 29:1701266

18.

Callister WD, Rethwisch DG (2018) Materials science and engineering: an introduction (Vol. 9). 8th edn. Wiley, New York, pp 203

19.

Gondal MA, Drmosh QA, Yamani ZH, Saleh TA (2009) Synthesis of ZnO₂ nanoparticles by laser ablation in liquid and their annealing transformation into ZnO nanoparticles. Appl Surf Sci 256:298–304

20.

Soni BH, Deshpande MP, Bhatt SV, Chaki SH, Sathe V (2013) X-ray diffraction, X-ray photoelectron spectroscopy, and raman spectroscopy of undoped and Mn-doped ZnO nanoparticles prepared by microwave irradiation. J Appl Spectrosc 79:901–907

21.

Dehimi M, Touam T, Chelouche A, Boudjouan F, Djouadi D, Solard J et al (2015) Effects of low Ag doping on physical and optical waveguide properties of highly oriented sol-gel ZnO thin films. Adv Condens Matter Phys 1–10

22.

Foecke T, Iadicola MA, Lin A, Banovic SW (2007) A method for direct measurement of multiaxial stress-strain curves in sheet metal. Metall Mater Trans A 38:306–313

23.

Ghosh R, Basak D, Fujihara S (2004) Effect of substrate-induced strain on the structural, electrical, and optical properties of polycrystalline ZnO thin films. J Appl Phys 96:2689–2692

24.

Podili S, Geetha D, Ramesh PS (2018) Electrochemical studies on Ni doped CuS nanostructures with cationic surfactant synthesized through a hydrothermal route. J Mater Sci Mater Electron 29:11167–11177

25.

Kumar A, Rahman S, Kazim SN, Ansari ZA, Ansari SG (2013) Application of glutathione coated ZnO nanoparticles to study the oxidative stress in bacterial cells. Mater Focus 2:148–154

26.

Nduna M, Rodriguez-Pascual M, Lewis AE (2013) Effect of dissolved precipitating ions on the settling characteristics of copper sulphide. J South Afr Inst Min Metall 113:00–00

27.

Ayodhya D, Venkatesham M, Santoshi Kumari A, Reddy GB, Ramakrishna D, Veerabhadram G (2016) Photocatalytic degradation of dye pollutants under solar, visible and UV lights using green synthesised CuS nanoparticles. J Exp Nanosci 11:418–432

28.

Lesyuk R, Klein E, Yaremchuk I, Klinke C (2018) Copper sulfide nanosheets with shape-tunable plasmonic properties in the NIR region. Nanoscale 10:20640–20651PubMedPubMedCentral

29.

Xie Y, Carbone L, Nobile C, Grillo V, D’Agostino S, Della Sala F et al (2013) Metallic-like stoichiometric copper sulfide nanocrystals: phase-and shape-selective synthesis, near-infrared surface plasmon resonance properties, and their modeling. ACS Nano 7:7352–7369PubMed

30.

Kriegel I, Scotognella F, Manna L (2017) Plasmonic doped semiconductor nanocrystals: properties, fabrication, applications and perspectives. Phys Rep 674:1–52

31.

Bilgili O (2019) The effects of Mn doping on the structural and optical properties of ZnO. Acta Phys Pol 136:460–66

32.

Karmakar R, Neogi SK, Banerjee A, Bandyopadhyay S (2012) Structural; morphological; optical and magnetic properties of Mn doped ferromagnetic ZnO thin film. Appl Surf Sci 263:671–677

33.

Al-Jawad SM, Sabeeh SH, Taha AA, Jassim HA (2019) Synthesis and characterization of Fe–ZnO thin films for antimicrobial activity. Surf Rev Lett 26:1850197

34.

AL-Jawad SM, Taha AA, Redha AM (2019) Studying the structural, morphological, and optical properties of CuS: Ni nanostructure prepared by a hydrothermal method for biological activity. J Solgel Sci Technol 91:310–323

35.

Taha AA, Al-Jawad SM, Salim MM (2018) Influence of titanium tetraisopropoxide concentration on the antibacterial activity of TiO₂ thin films. Surf Rev Lett 25:1850111

36.

Taha AA, Al-Jawad SM, Redha AM (2019) Preparation and characterization of nanostructure CuS for biological activity. Mod Phys Lett B 33:1950374

37.

Al-Jawad SM, Rafic SN, Muhsen MM (2017) Preparation and characterization of polyaniline–cadmium sulfide nanocomposite for gas sensor application. Mod Phys Lett B 31:1750234

38.

AL-Jawad SM, Sabeeh SH, Taha AA, Jassim HA (2018) Studying structural, morphological and optical properties of nanocrystalline ZnO: Ag films prepared by sol–gel method for antimicrobial activity. J Solgel Sci Technol 87:362–371

39.

Al-Zuhery AM , Al-Jawad SM, Al-Mousoi AK (2017) The effect of PbS thickness on the performance of CdS/PbS solar cell prepared by CSP. Optik 130:666–672

40.

Nemade KR, Waghuley DS (2015) Band gap engineering of CuS nanoparticles for artificial photosynthesis. Mater Sci Semicond 39:781–785

41.

Singh M, Goyal M, Devlal K (2018) Size and shape effects on the band gap of semiconductor compound nanomaterials. J Taibah Univ Sci 12:470–475

42.

Sreelekha N, Subramanyam K, Reddy DA, Murali G, Ramu S, Varma KR et al (2016) Structural, optical, magnetic and photocatalytic properties of Co doped CuS diluted magnetic semiconductor nanoparticles. Appl Surf Sci 378:330–340

43.

Fathima AS, Sivaguru N, Kumar VS (2016) Investigation on optical properties of CuS and Zn doped CuS thin films by chemical bath deposition method. IOSR J App Phy (IOSR-JAP) 8:13–16

44.

Kandasamy N, Saravanan S (2013) Synthesis and optical properties of vanadium doped covellite nanostructure by wet chemical method. In International conference on advanced nanomaterials & emerging engineering technologies (pp. 52–54) IEEE, 24th-26th, July, organized by Sathyabama University, Chennai, India in association with DRDO, New Delhi, India

45.

Freeda MA, Mahadevan CK (2013) Effect of Zn2+ dopping on CuS nanocrystals. Mater Sci Ind J 9:283–288

46.

Sreelekha N, Subramanyam K, Reddy DA, Murali G, Varma KR, Vijayalakshmi RP (2016) Efficient photocatalytic degradation of rhodamine-B by Fe doped CuS diluted magnetic semiconductor nanoparticles under the simulated sunlight irradiation. Solid State Sci 62:71–81

47.

Podili S, Geetha D, Ramesh PS (2017) One-pot synthesis of CTAB stabilized mesoporous cobalt doped CuS nano flower with enhanced pseudocapacitive behavior. J Mater Sci Mater Electron 28:15387–15397

48.

Mofokeng TP, Moloto MJ, Shumbula PM, Nyamukamba P, Mubiayi PK, Takaidza S et al (2018) Antimicrobial activity of amino acid-capped zinc and copper sulphide nanoparticles. J Nanotechnol 1–9

49.

Getie S, Belay A, Chandra Reddy AR, Belay Z (2017) Synthesis and characterizations of zinc oxide nanoparticles for antibacterial applications. J Nanomed Nanotechno S 8:1–8

50.

Brayner R, Ferrari-Iliou R, Brivois N, Djediat S, Benedetti MF, Fiévet F (2006) Toxicological impact studies based on Escherichia coli bacteria in ultrafine ZnO nanoparticles colloidal medium. Nano Lett 6:866–870PubMed

51.

Stoimenov PK, Klinger RL, Marchin GL, Klabunde KJ (2002) Metal oxide nanoparticles as bactericidal agents. Langmuir 18:6679–6686

52.

Hubenthal F, Hendrich C, Träger F (2010) Damping of the localized surface plasmon polariton resonance of gold nanoparticles. Appl Phys B 100:225–230

53.

Abadeer NS, Murphy CJ (2016) Recent progress in cancer thermal therapy using gold nanoparticles. J Phys Chem C 120:4691–4716

Titel: NIR laser-conjugated glutathione-coated Mn-doped CuS nanoprisms as photothermal agent for cancer treatment
verfasst von: Mustafa M. Muhsen
Selma M. H. Al-Jawad
Ali A. Taha
Publikationsdatum: 01.12.2023
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 1/2023
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-022-03668-z

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NIR laser-conjugated glutathione-coated Mn-doped CuS nanoprisms as photothermal agent for cancer treatment

Abstract

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

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