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Lasers in Medical Science

Erschienen in:

01.12.2023 | Letter to the Editor

Photodynamic therapy to photochemical internalization: a clinician’s insight into evolving cancer therapies

verfasst von: Waseem Jerjes

Erschienen in: Lasers in Medical Science | Ausgabe 1/2023

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Excerpt

Over the past two decades, photodynamic therapy (PDT) has carved out a significant niche in clinical research. Often dubbed the “fourth modality,” following surgery, radiotherapy, and chemotherapy, PDT operates on the principle of harnessing a photosensitizer drug’s synergy with specific wavelength light and tissue oxygen to treat tissue malignancies [1]. …

Ramsay D, Stevenson H, Jerjes W (2021) From basic mechanisms to clinical research: photodynamic therapy applications in head and neck malignancies and vascular anomalies. J Clin Med 10(19):4404CrossRefPubMedPubMedCentral

Fayter D, Corbett M, Heirs M, Fox D, Eastwood A (2010) A systematic review of photodynamic therapy in the treatment of pre-cancerous skin conditions, Barrett’s oesophagus and cancers of the biliary tract, brain, head and neck, lung, oesophagus and skin. Health Technol Assess 14(37):1–288CrossRefPubMed

Jerjes W, Upile T, Hamdoon Z, Alexander Mosse C, Morcos M, Hopper C (2011) Photodynamic therapy outcome for T1/T2 N0 oral squamous cell carcinoma. Lasers Surg Med 43(6):463–469CrossRefPubMed

Jerjes W, Hamdoon Z, Berg K, Høgset A, Hopper C (2021) Squamous cell carcinoma of the ear treated by photochemical internalization. Photodiagnosis Photodyn Ther 36:102528CrossRefPubMed

Jerjes W, Hamdoon Z, Berg K, Høgset A, Hopper C (2020) Apparent complete response of a treatment refractory and recurrent squamous cell carcinoma lesion to photochemical internalization: a clinical case study. Photochem Photobiol 96(3):680–683CrossRefPubMed

Sultan AA, Jerjes W, Berg K, Høgset A, Mosse CA, Hamoudi R, Hamdoon Z, Simeon C, Carnell D, Forster M, Hopper C (2016) Disulfonated tetraphenyl chlorin (TPCS2a)-induced photochemical internalisation of bleomycin in patients with solid malignancies: a phase 1, dose-escalation, first-in-man trial. Lancet Oncol 17(9):1217–1229CrossRefPubMed

Jerjes W, Theodossiou TA, Hirschberg H, Høgset A, Weyergang A, Selbo PK, Hamdoon Z, Hopper C, Berg K (2020) Photochemical internalization for intracellular drug delivery. From basic mechanisms to clinical research. J Clin Med 9(2):528CrossRefPubMedPubMedCentral

Titel: Photodynamic therapy to photochemical internalization: a clinician’s insight into evolving cancer therapies
verfasst von: Waseem Jerjes
Publikationsdatum: 01.12.2023
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 1/2023
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-023-03873-4

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Photodynamic therapy to photochemical internalization: a clinician’s insight into evolving cancer therapies

Excerpt

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Excerpt

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