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Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery 1/2023

17.12.2022 | Original Article

Relationship Between Lipid Profile and Sensorineural Hearing Loss: An Institution Based Study

verfasst von: Rupali Sharma, Gopika Kalsotra, Anchal Gupta, Vikas Mahajan, Dev Raj, Parmod Kalsotra, Arun Manhas

Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery | Sonderheft 1/2023

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Abstract

Sensorineural hearing loss is the most frequent problem worldwide and is the most neglected condition. Thus, it is essential to understand the etiology and pathophysiology of SNHL. The main objective of the study is to find whether serum lipid parameters have any correlation with SNHL. 68 patients within the age group of 20–60 years with clinically diagnosed sensorineural hearing loss were included in this study. Informed written consent, otoscopy, pure tone audiometry were done on all patients. The subjects were subjected to Serum lipid profile. The mean age of subjects in this study was 53.25 ± 13.78 years and male to female ratio was found to be 1.125:1. The serum total cholesterol and serum triglyceride also showed significant relationship with the degree of hearing loss (p value < 0.001). With an increase in the serum LDL there was increase in the severity of hearing loss which was statistically significant (p value < 0.001) where as serum HDL level showed statistically insignificant and negative correlation with severity of hearing loss. Serum lipid profile can be used as important biomarker for assessing the severity of hearing loss. Subjects with deranged lipid parameters had higher degress of hearing impairement.
Literatur
1.
Zurück zum Zitat Garg S, Chadha S, Malhotra S et al (2009) Deafness: burden, prevention and control in India. Natl Med J India 22(2):79–81PubMed Garg S, Chadha S, Malhotra S et al (2009) Deafness: burden, prevention and control in India. Natl Med J India 22(2):79–81PubMed
2.
Zurück zum Zitat Mathers C, Smith A, Concha M (2000) Global burden of hearing loss in the year 2000. Global Burd Dis 18(4):1–30 Mathers C, Smith A, Concha M (2000) Global burden of hearing loss in the year 2000. Global Burd Dis 18(4):1–30
3.
Zurück zum Zitat Kim JS, Lopez I, DiPatre PL et al (1999) Internal auditoryartery infarction: clinicopathologic correlation. Neurology 52:40–44 Kim JS, Lopez I, DiPatre PL et al (1999) Internal auditoryartery infarction: clinicopathologic correlation. Neurology 52:40–44
4.
Zurück zum Zitat Lee JS, Kim DH, Lee HJ et al (2015) Lipidprofiles and obesity as potential risk factors of sudden sensorineural hearing loss. PLoS ONE 10:e0122496CrossRefPubMedPubMedCentral Lee JS, Kim DH, Lee HJ et al (2015) Lipidprofiles and obesity as potential risk factors of sudden sensorineural hearing loss. PLoS ONE 10:e0122496CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Jones NS, Davis A (1999) A prospective case-control study of patients presenting with idiopathic sensorineuralhearing loss to examine the relationship between hyperlipidemia and sensorineural hearing loss. Clin Otolaryngol Allied Sci 24(6):531–536CrossRef Jones NS, Davis A (1999) A prospective case-control study of patients presenting with idiopathic sensorineuralhearing loss to examine the relationship between hyperlipidemia and sensorineural hearing loss. Clin Otolaryngol Allied Sci 24(6):531–536CrossRef
6.
Zurück zum Zitat Xipeng L, Ruiyu L, MengL et al (2013) Effects ofdiabetes on hearing and cochlear structures. J Otology 8:82–87CrossRef Xipeng L, Ruiyu L, MengL et al (2013) Effects ofdiabetes on hearing and cochlear structures. J Otology 8:82–87CrossRef
7.
Zurück zum Zitat Kuhn M, Heman-Ackah SE, Shaikh JA et al (2011) Sudden sensorineuralhearing loss: a review of diagnosis, treatment, and prognosis. Trends Amplif 15:91–105CrossRefPubMedPubMedCentral Kuhn M, Heman-Ackah SE, Shaikh JA et al (2011) Sudden sensorineuralhearing loss: a review of diagnosis, treatment, and prognosis. Trends Amplif 15:91–105CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Chau JK, Lin JR, Atashband S et al (2010) Systematic review of the evidence for the etiology of adult sudden sensorineural hearing loss. Laryngoscope 120:1011–1021PubMed Chau JK, Lin JR, Atashband S et al (2010) Systematic review of the evidence for the etiology of adult sudden sensorineural hearing loss. Laryngoscope 120:1011–1021PubMed
9.
Zurück zum Zitat Brusis T (2011) Sensorineural hearing loss after dull head injury or concussiontrauma. Laryngorhinootologie 90:73–80CrossRefPubMed Brusis T (2011) Sensorineural hearing loss after dull head injury or concussiontrauma. Laryngorhinootologie 90:73–80CrossRefPubMed
10.
Zurück zum Zitat Hoet P, Lison D (2008) Ototoxicity of toluene and styrene: state of current knowledge. Crit Rev Toxicol 38:127–170CrossRefPubMed Hoet P, Lison D (2008) Ototoxicity of toluene and styrene: state of current knowledge. Crit Rev Toxicol 38:127–170CrossRefPubMed
11.
12.
Zurück zum Zitat Lowry LD, Isaacson SR (1978) Study of 100 patients with bilateral sensorineural hearing loss for lipid abnormalities. Ann Otol 87:404–408 Lowry LD, Isaacson SR (1978) Study of 100 patients with bilateral sensorineural hearing loss for lipid abnormalities. Ann Otol 87:404–408
13.
Zurück zum Zitat Wright A (1997) Anatomy and ultrastructure of the human ear. In: Scott BrownsOtolaryngology Basic sciences, 6th edn. Butterworth, London Wright A (1997) Anatomy and ultrastructure of the human ear. In: Scott BrownsOtolaryngology Basic sciences, 6th edn. Butterworth, London
14.
Zurück zum Zitat Gale J, Forge A (2018) Anatomy of the cochlea and vestibular system: relatingultrastructure to function. In: Watkinson JC, Clarke RW (eds) Scott-Brown’s otolaryngology and head and neck surgery, 8th edn. CRC Press, London Gale J, Forge A (2018) Anatomy of the cochlea and vestibular system: relatingultrastructure to function. In: Watkinson JC, Clarke RW (eds) Scott-Brown’s otolaryngology and head and neck surgery, 8th edn. CRC Press, London
15.
Zurück zum Zitat Geberie A, Gnanasekaran N, Menon M (2018) Evaluation of lipid profile and hematological parameters in hypertensive patients. Laboratory-based cross-sectional study. SAGE Open Med 6:2050312118756663 Geberie A, Gnanasekaran N, Menon M (2018) Evaluation of lipid profile and hematological parameters in hypertensive patients. Laboratory-based cross-sectional study. SAGE Open Med 6:2050312118756663
16.
Zurück zum Zitat Mudhol RS, Patwegar A (2019) Lipid profile in patients with sensorineural hearing loss- one year observational study in a tertiary care centre. Madridge J Otorhinolaryngol 4(1):77–80CrossRef Mudhol RS, Patwegar A (2019) Lipid profile in patients with sensorineural hearing loss- one year observational study in a tertiary care centre. Madridge J Otorhinolaryngol 4(1):77–80CrossRef
17.
Zurück zum Zitat Handique G, Das M, Gogoi C et al (2016) A study of serum lipid profile in clinically diagnosed patient of sensorineural hearing loss. Int J Adv Res 4(9):1571–1576CrossRef Handique G, Das M, Gogoi C et al (2016) A study of serum lipid profile in clinically diagnosed patient of sensorineural hearing loss. Int J Adv Res 4(9):1571–1576CrossRef
18.
Zurück zum Zitat Anil HT, Shazia (2016) A study of relationship between serum lipids andSensorineural hearing loss. JMSCR 4(7):11570–11573 Anil HT, Shazia (2016) A study of relationship between serum lipids andSensorineural hearing loss. JMSCR 4(7):11570–11573
19.
Zurück zum Zitat Lee FS, Matthews LJ, Mills JH et al (1998) Analysis of bloodchemistry and hearing levels in a sample of older persons. Ear Hear 19(3):180–190CrossRefPubMed Lee FS, Matthews LJ, Mills JH et al (1998) Analysis of bloodchemistry and hearing levels in a sample of older persons. Ear Hear 19(3):180–190CrossRefPubMed
20.
Zurück zum Zitat Friederich G, Pilger E (1981) Lipoproteins in cochleovestibular disorders. ArchOtorhinolaryngol 232(2):101–105 Friederich G, Pilger E (1981) Lipoproteins in cochleovestibular disorders. ArchOtorhinolaryngol 232(2):101–105
21.
Zurück zum Zitat Gates GA, Cobb JL, D’Agostino RB et al (1993) The relation of hearing in theelderly to the presence of cardiovascular disease and cardiovascular risk factors. Arch Otolaryngol Head Neck Surg 119(2):156–161CrossRefPubMed Gates GA, Cobb JL, D’Agostino RB et al (1993) The relation of hearing in theelderly to the presence of cardiovascular disease and cardiovascular risk factors. Arch Otolaryngol Head Neck Surg 119(2):156–161CrossRefPubMed
Metadaten
Titel
Relationship Between Lipid Profile and Sensorineural Hearing Loss: An Institution Based Study
verfasst von
Rupali Sharma
Gopika Kalsotra
Anchal Gupta
Vikas Mahajan
Dev Raj
Parmod Kalsotra
Arun Manhas
Publikationsdatum
17.12.2022
Verlag
Springer India
Erschienen in
Indian Journal of Otolaryngology and Head & Neck Surgery / Ausgabe Sonderheft 1/2023
Print ISSN: 2231-3796
Elektronische ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-022-03328-2

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