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Erschienen in: Lasers in Medical Science 1/2023

01.12.2023 | Original Article

Seven-year corneal densitometry changes after small incision lenticule extraction and femtosecond laser-assisted in situ keratomileusis

verfasst von: Tian Han, Luoli Zhang, Yangyi Huang, Yang Shen, Xingtao Zhou, Ye Xu

Erschienen in: Lasers in Medical Science | Ausgabe 1/2023

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Abstract

This study aims to investigate the 7-year changes in corneal densitometry (CD) after small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (FS-LASIK). Forty-two eyes undergoing SMILE and thirty-one undergoing FS-LASIK were included in this retrospective study. CD was measured preoperatively and at 3 and 7 years postoperatively. Three concentric radial zones (0–2, 2–6, and 6–10 mm) of three different corneal depths (anterior 120 μm, posterior 60 μm, and central layer) were analyzed. In all three zones of the three corneal layers, no significant difference in CD was found between the two groups preoperatively and at 3 and 7 years postoperatively (all P > 0.05). All CD values in the three zones of the anterior and central layers significantly declined at 3 years postoperatively (all P < 0.001), and then increased at 7 years postoperatively compared to corresponding 3-year values (all P < 0.01). In the posterior layer, CD values in the 0–2-mm and 2–6-mm zones decreased at 3 years postoperatively (all P < 0.01) and continued to decrease at 7 years postoperatively (all P < 0.01). Similar CD trends were observed after SMILE and FS-LASIK. Posterior layer CD showed a decrease throughout the study period. In the anterior and central layers, CD values decreased and then increased at 7 years postoperatively. The transparency changes might have been due to age-related three-dimensional growth of collagen fibers and wound-healing reactions.
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Metadaten
Titel
Seven-year corneal densitometry changes after small incision lenticule extraction and femtosecond laser-assisted in situ keratomileusis
verfasst von
Tian Han
Luoli Zhang
Yangyi Huang
Yang Shen
Xingtao Zhou
Ye Xu
Publikationsdatum
01.12.2023
Verlag
Springer London
Erschienen in
Lasers in Medical Science / Ausgabe 1/2023
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-023-03850-x

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