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Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology 12/2023

15.05.2023 | Review Article

Success rate of external, endonasal, and transcanalicular laser DCR with or without silicone stent intubation for NLD obstruction: a network meta-analysis of randomized controlled trials

verfasst von: Cem Evereklioglu, Hidayet Sener, Osman Ahmet Polat, Hatice Kubra Sonmez, Ayse Busra Gunay Sener, Fatih Horozoglu

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 12/2023

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Abstract

Purpose

To define and compare the effectiveness of external dacryocystorhinostomy (EX-DCR), endonasal (EN-DCR), and transcanalicular laser-assisted (TL-DCR) with or without silicone stent (S) intubation.

Methods

Studies were retrieved from PubMed, Scopus, and WoS. Frequentist and Bayesian network meta-analyses were performed and pooled estimations were expressed as risk ratio (RR). We included all original investigations of prospective, randomized controlled trials comparing success rate for any two of the following six surgical procedures: standard EX-DCR with or without S, cold EN-DCR with or without S, and TL-DCR with or without S. The primary outcome measure was the objective success rate.

Results

Thirty-two studies with 3277 cases were included in the final quantitative analysis. TL-DCR with S was inferior to EN-DCR with S (RR: 1.20; 95% CI: 1.05–1.37), EX-DCR with S (RR: 1.17 95% CI: 1.05–1.29), EN-DCR without S (RR: 1.18; 95% CI: 1.03–1.35), and EX-DCR without S (RR: 1.15; 95%CI: 1.05–1.26) in frequentist statistics. No other statistical difference was found between other surgeries. When we excluded studies with additional interventions (nasal and revision surgery) for sensitivity analysis, 23 studies with 2468 cases were included to analysis. The success rates of TL-DCR with S and EN-DCR without S became similar (RR: 1.14 95% CI: 0.99–1.30) but there was no change in other outcomes. Similar results were found in Bayesian statistics. The surface under the cumulative ranking curve was higher for EN-DCR with S (0.75), whereas it was higher for EX-DCR with S (0.56) after sensitivity analysis.

Conclusion

Between endoscopic and external and transcanalicular laser without S procedures, there is no statistical difference. The rank probability showed that EN-DCR with S was a more appropriate surgical option when patients with nasal disease were included, whereas EX-DCR with S was a more appropriate surgical option when patients with nasal disease were excluded from the analysis.
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Metadaten
Titel
Success rate of external, endonasal, and transcanalicular laser DCR with or without silicone stent intubation for NLD obstruction: a network meta-analysis of randomized controlled trials
verfasst von
Cem Evereklioglu
Hidayet Sener
Osman Ahmet Polat
Hatice Kubra Sonmez
Ayse Busra Gunay Sener
Fatih Horozoglu
Publikationsdatum
15.05.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 12/2023
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-023-06089-y

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