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Lasers in Medical Science

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01.12.2024 | Original Article

Theoretical and experimental study on the photothermal effect of palladium nanoparticles based on a finite element model

verfasst von: Dong Li, Jing Feng, Xinzhi Zhang, Penghui Zhao, Linzhuang Xing, Bin Chen, Lihong Fan

Erschienen in: Lasers in Medical Science | Ausgabe 1/2024

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Abstract

Palladium nanoparticles (Pd NPs) show significant promise as agents for the photothermal treatment of tumors due to their high photothermal conversion efficiency and thermal stability. theoretical calculations were conducted to investigate the electric field and solid heat conduction of Pd NPs with various sizes and particle distances, aiming to achieve the maximum photothermal conversion efficiency during laser irradiation. Subsequently, Pd NPs with optimal size and structure were synthesized. In vitro and in vivo experiments were conducted to evaluate photothermal conversion. The theoretical results indicated that a peak temperature of 90.12 °C is achieved when the side length is 30 nm with a distance of 2 nm. In vitro experiments demonstrated that the photothermal conversion efficiency of Pd NPs can reach up to 61.9%. in vivo experiments revealed that injecting Pd NPs into blood vessels can effectively reduce the number of laser pulses by 22.22%, thereby inducing obvious vasoconstriction.

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Titel: Theoretical and experimental study on the photothermal effect of palladium nanoparticles based on a finite element model
verfasst von: Dong Li
Jing Feng
Xinzhi Zhang
Penghui Zhao
Linzhuang Xing
Bin Chen
Lihong Fan
Publikationsdatum: 01.12.2024
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 1/2024
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-023-03952-6

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Theoretical and experimental study on the photothermal effect of palladium nanoparticles based on a finite element model

Abstract

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

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