Skip to main content
Erschienen in: Lasers in Medical Science 1/2023

01.12.2023 | Original Article

Effect of low-level laser therapy on orthodontic tooth movement during miniscrew-supported maxillary molar distalization in humans: a single-blind, randomized controlled clinical trial

verfasst von: Beren Özsoy, Kemal Güldüren, Beste Kamiloğlu

Erschienen in: Lasers in Medical Science | Ausgabe 1/2023

Einloggen, um Zugang zu erhalten

Abstract

To investigate the effect of low-level laser therapy (LLLT) on orthodontic tooth movement during maxillary molar distalization over a 12-week observation period. Twenty patients were enrolled in this clinical trial. On the 0th, 3rd, 7th, 14th, 21st, 42nd, and 63rd days following the initial activation of the distalization appliance, laser therapy was applied in a total of 16 different points of the first and second molars for 10 s per point to the randomly determined molar region of the individuals in the intervention group. The amount of molar distalization was measured using digital scans of the three-dimensional (3D) digital models obtained during the 3rd, 6th, 9th, and 12th weeks. The amount of tooth movement on the laser-applied side of subjects in the intervention group was significantly greater than those in the contralateral and control groups at all time intervals (p < 0.001). The amount of tooth movement between the contralateral side of the intervention group and the control group was determined to be statistically insignificant (p > 0.05) at all time intervals. The laser-treated molars of the subjects in the intervention group moved 1.22 times more than the molars in the contralateral side and in the control group in 12 weeks. The rate of tooth movement in the laser, contralateral, and control groups was 0.033, 0.027, and 0.027 mm/day, respectively. Although LLLT was found to be statistically significant in terms of accelerating tooth movement, the effect of LLLT is not considered to be clinically significant. This trial was retrospectively registered (September 22, 2022) at Clinical-Trials.gov (Ref no: NCT05550168).
Literatur
1.
Zurück zum Zitat Buschang PH, Campbell PM, Ruso S (2012) Accelerating tooth movement with corticotomies: is it possible and desirable? Seminars in Orthodontics 18(4):286–294 Buschang PH, Campbell PM, Ruso S (2012) Accelerating tooth movement with corticotomies: is it possible and desirable? Seminars in Orthodontics 18(4):286–294
2.
Zurück zum Zitat Mavreas D, Athanasiou AE (2008) Factors affecting the duration of orthodontic treatment: a systematic review. Eur J Orthod 30(4):386–395PubMed Mavreas D, Athanasiou AE (2008) Factors affecting the duration of orthodontic treatment: a systematic review. Eur J Orthod 30(4):386–395PubMed
3.
Zurück zum Zitat Alikhani M, Alansari S, Sangsuwon C et al (2015) Micro-osteoperforations: minimally invasive accelerated tooth movement. Seminars in Orthodontics 21:162–169 Alikhani M, Alansari S, Sangsuwon C et al (2015) Micro-osteoperforations: minimally invasive accelerated tooth movement. Seminars in Orthodontics 21:162–169
4.
Zurück zum Zitat Segal GR, Schiffman PH, Tuncay OC (2004) Meta analysis of the treatment-related factors of external apical root resorption. Orthod Craniofac Res 7(2):71–78PubMed Segal GR, Schiffman PH, Tuncay OC (2004) Meta analysis of the treatment-related factors of external apical root resorption. Orthod Craniofac Res 7(2):71–78PubMed
5.
Zurück zum Zitat Ristic M, Svabic M, Sasic M et al (2007) Clinical and microbiological effects of fixed orthodontic appliances on periodontal tissues in adolescents. Orthod Craniofac Res 10(4):187–195PubMed Ristic M, Svabic M, Sasic M et al (2007) Clinical and microbiological effects of fixed orthodontic appliances on periodontal tissues in adolescents. Orthod Craniofac Res 10(4):187–195PubMed
6.
Zurück zum Zitat Ge M, He W, Chen J et al (2015) Efficacy of low-level laser therapy for accelerating tooth movement during orthodontic treatment: a systematic review and meta-analysis. Lasers Med Sci 30(5):1609–1618PubMed Ge M, He W, Chen J et al (2015) Efficacy of low-level laser therapy for accelerating tooth movement during orthodontic treatment: a systematic review and meta-analysis. Lasers Med Sci 30(5):1609–1618PubMed
7.
Zurück zum Zitat Krishnan V, Davidovitch ZE (2006) Cellular, molecular, and tissue-level reactions to orthodontic force. Am J Orthod Dentofac Orthop 129(4):469-e1 Krishnan V, Davidovitch ZE (2006) Cellular, molecular, and tissue-level reactions to orthodontic force. Am J Orthod Dentofac Orthop 129(4):469-e1
8.
Zurück zum Zitat Patil AK, Keluskar KM, Gaitonde SD (2005) The clinical application of prostaglandin E1 on orthodontic tooth movement-a clinical trial. Journal of Indian Orthodontic Society 39(2):91–98 Patil AK, Keluskar KM, Gaitonde SD (2005) The clinical application of prostaglandin E1 on orthodontic tooth movement-a clinical trial. Journal of Indian Orthodontic Society 39(2):91–98
9.
Zurück zum Zitat Showkatbakhsh R, Jamilian A, Showkatbakhsh M (2010) The effect of pulsed electromagnetic fields on the acceleration of tooth movement. World Journal of Orthodontics 11(4):e52–e56PubMed Showkatbakhsh R, Jamilian A, Showkatbakhsh M (2010) The effect of pulsed electromagnetic fields on the acceleration of tooth movement. World Journal of Orthodontics 11(4):e52–e56PubMed
10.
Zurück zum Zitat Pavlin D, Anthony R, Raj V et al (2015) Cyclic loading (vibration) accelerates tooth movement in orthodontic patients: a double-blind, randomized controlled trial. Seminars in Orthodontics 21:187–94 Pavlin D, Anthony R, Raj V et al (2015) Cyclic loading (vibration) accelerates tooth movement in orthodontic patients: a double-blind, randomized controlled trial. Seminars in Orthodontics 21:187–94
11.
Zurück zum Zitat Doshi-Mehta G, Bhad-Patil WA (2012) Efficacy of low-intensity laser therapy in reducing treatment time and orthodontic pain: a clinical investigation. Am J Orthod Dentofac Orthop 141(3):289–297 Doshi-Mehta G, Bhad-Patil WA (2012) Efficacy of low-intensity laser therapy in reducing treatment time and orthodontic pain: a clinical investigation. Am J Orthod Dentofac Orthop 141(3):289–297
12.
Zurück zum Zitat da Silva Sousa MV, Scanavini MA, Sannomiya EK et al (2011) Influence of low-level laser on the speed of orthodontic movement. Photomed Laser Surg 29(3):191–196 da Silva Sousa MV, Scanavini MA, Sannomiya EK et al (2011) Influence of low-level laser on the speed of orthodontic movement. Photomed Laser Surg 29(3):191–196
13.
Zurück zum Zitat Türker G, Yavuz İ, Gönen ZB (2021) Which method is more effective for accelerating canine distalization short term, low-level laser therapy or piezocision? a split-mouth study. Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopädie 82(4):236–245PubMed Türker G, Yavuz İ, Gönen ZB (2021) Which method is more effective for accelerating canine distalization short term, low-level laser therapy or piezocision? a split-mouth study. Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopädie 82(4):236–245PubMed
14.
Zurück zum Zitat Üretürk SE, Saraç M, Fıratlı S et al (2017) The effect of low-level laser therapy on tooth movement during canine distalization. Lasers Med Sci 32(4):757–764PubMed Üretürk SE, Saraç M, Fıratlı S et al (2017) The effect of low-level laser therapy on tooth movement during canine distalization. Lasers Med Sci 32(4):757–764PubMed
15.
Zurück zum Zitat Genc G, Kocadereli İ, Tasar F et al (2013) Effect of low-level laser therapy (LLLT) on orthodontic tooth movement. Lasers Med Sci 28(1):41–47PubMed Genc G, Kocadereli İ, Tasar F et al (2013) Effect of low-level laser therapy (LLLT) on orthodontic tooth movement. Lasers Med Sci 28(1):41–47PubMed
16.
Zurück zum Zitat AlSayed Hasan MMA, Sultan K, Hamadah O (2016) Low-level laser therapy effectiveness in accelerating orthodontic tooth movement: a randomized controlled clinical trial. Angle Orthod 87(4):499–504PubMedPubMedCentral AlSayed Hasan MMA, Sultan K, Hamadah O (2016) Low-level laser therapy effectiveness in accelerating orthodontic tooth movement: a randomized controlled clinical trial. Angle Orthod 87(4):499–504PubMedPubMedCentral
17.
Zurück zum Zitat Sousa MVS, Pinzan A, Consolaro A et al (2014) Systematic literature review: influence of low-level laser on orthodontic movement and pain control in humans. Photomed Laser Surg 32(11):592–599PubMed Sousa MVS, Pinzan A, Consolaro A et al (2014) Systematic literature review: influence of low-level laser on orthodontic movement and pain control in humans. Photomed Laser Surg 32(11):592–599PubMed
18.
Zurück zum Zitat Gil APS, Haas OL Jr, Méndez-Manjón I et al (2018) Alveolar corticotomies for accelerated orthodontics: a systematic review. J Cranio-Maxillofacial Surg 46(3):438–445 Gil APS, Haas OL Jr, Méndez-Manjón I et al (2018) Alveolar corticotomies for accelerated orthodontics: a systematic review. J Cranio-Maxillofacial Surg 46(3):438–445
19.
Zurück zum Zitat Uzuner FD, Darendeliler N (2013) Dentoalveolar surgery techniques combined with orthodontic treatment: a literature review. Eur J Dentistry 7(02):257–265 Uzuner FD, Darendeliler N (2013) Dentoalveolar surgery techniques combined with orthodontic treatment: a literature review. Eur J Dentistry 7(02):257–265
20.
Zurück zum Zitat Alfawal AM, Hajeer MY, Ajaj MA et al (2016) Effectiveness of minimally invasive surgical procedures in the acceleration of tooth movement: a systematic review and meta-analysis. Prog Orthod 17(1):1–12 Alfawal AM, Hajeer MY, Ajaj MA et al (2016) Effectiveness of minimally invasive surgical procedures in the acceleration of tooth movement: a systematic review and meta-analysis. Prog Orthod 17(1):1–12
21.
Zurück zum Zitat Arqub SA, Gandhi V, Iverson MG et al (2021) The effect of the local administration of biological substances on the rate of orthodontic tooth movement: a systematic review of human studies. Prog Orthod 22(1):1–12 Arqub SA, Gandhi V, Iverson MG et al (2021) The effect of the local administration of biological substances on the rate of orthodontic tooth movement: a systematic review of human studies. Prog Orthod 22(1):1–12
22.
Zurück zum Zitat Kalemaj Z, DebernardI CL, Buti J (2015) Efficacy of surgical and non-surgical interventions on accelerating orthodontic tooth movement: a systematic review. Eur J Oral Implantol 8(1):9–24PubMed Kalemaj Z, DebernardI CL, Buti J (2015) Efficacy of surgical and non-surgical interventions on accelerating orthodontic tooth movement: a systematic review. Eur J Oral Implantol 8(1):9–24PubMed
23.
Zurück zum Zitat Dubey I, Khera A, Raghav P (2021) Role of vibrations in orthodontics. Int J Appl Dental Sci 7(2):70–73 Dubey I, Khera A, Raghav P (2021) Role of vibrations in orthodontics. Int J Appl Dental Sci 7(2):70–73
24.
Zurück zum Zitat Sun G, Tunér J (2004) Low-level laser therapy in dentistry. Dental Clin 48(4):1061–1076 Sun G, Tunér J (2004) Low-level laser therapy in dentistry. Dental Clin 48(4):1061–1076
25.
Zurück zum Zitat Saito S, Shimizu N (1997) Stimulatory effects of low-power laser irradiation on bone regeneration in midpalatal suture during expansion in the rat. Am J Orthod Dentofac Orthop 111(5):525–532 Saito S, Shimizu N (1997) Stimulatory effects of low-power laser irradiation on bone regeneration in midpalatal suture during expansion in the rat. Am J Orthod Dentofac Orthop 111(5):525–532
26.
Zurück zum Zitat Yoshida T, Yamaguchi M, Utsunomiya T et al (2009) Low-energy laser irradiation accelerates the velocity of tooth movement via stimulation of the alveolar bone remodeling. Orthod Craniofac Res 12(4):289–298PubMed Yoshida T, Yamaguchi M, Utsunomiya T et al (2009) Low-energy laser irradiation accelerates the velocity of tooth movement via stimulation of the alveolar bone remodeling. Orthod Craniofac Res 12(4):289–298PubMed
27.
Zurück zum Zitat Kawasaki K, Shimizu N (2000) Effects of low-energy laser irradiation on bone remodeling during experimental tooth movement in rats. Lasers Surg Med 26(3):282–291PubMed Kawasaki K, Shimizu N (2000) Effects of low-energy laser irradiation on bone remodeling during experimental tooth movement in rats. Lasers Surg Med 26(3):282–291PubMed
28.
Zurück zum Zitat Yamaguchi M, Fujita S, Yoshida T et al (2007) Low-energy laser irradiation stimulates the tooth movement velocity via expression of M-CSF and c-fms. Orthodontic Waves 66(4):139–148 Yamaguchi M, Fujita S, Yoshida T et al (2007) Low-energy laser irradiation stimulates the tooth movement velocity via expression of M-CSF and c-fms. Orthodontic Waves 66(4):139–148
29.
Zurück zum Zitat Fujita S, Yamaguchi M, Utsunomiya T et al (2008) Low-energy laser stimulates tooth movement velocity via expression of RANK and RANKL. Orthod Craniofac Res 11(3):143–155PubMed Fujita S, Yamaguchi M, Utsunomiya T et al (2008) Low-energy laser stimulates tooth movement velocity via expression of RANK and RANKL. Orthod Craniofac Res 11(3):143–155PubMed
30.
Zurück zum Zitat Oliveira DD, Oliveira BF, Soares RV (2010) Alveolar corticotomies in orthodontics: indications and effects on tooth movement. Dental Press J Orthodontics 15:144–157 Oliveira DD, Oliveira BF, Soares RV (2010) Alveolar corticotomies in orthodontics: indications and effects on tooth movement. Dental Press J Orthodontics 15:144–157
31.
Zurück zum Zitat Gulduren K, Tumer H, Oz U (2020) Effects of micro-osteoperforations on intraoral miniscrew anchored maxillary molar distalization. J Orofacial Orthopedics/Fortschritte der Kieferorthopädie 81(2):126–141 Gulduren K, Tumer H, Oz U (2020) Effects of micro-osteoperforations on intraoral miniscrew anchored maxillary molar distalization. J Orofacial Orthopedics/Fortschritte der Kieferorthopädie 81(2):126–141
32.
Zurück zum Zitat Seifi M, Shafeei HA, Daneshdoost S et al (2007) Effects of two types of low-level laser wave lengths (850 and 630 nm) on the orthodontic tooth movements in rabbits. Lasers Med Sci 22(4):261–264PubMed Seifi M, Shafeei HA, Daneshdoost S et al (2007) Effects of two types of low-level laser wave lengths (850 and 630 nm) on the orthodontic tooth movements in rabbits. Lasers Med Sci 22(4):261–264PubMed
33.
Zurück zum Zitat Limpanichkul W, Godfrey K, Srisuk N et al (2006) Effects of low-level laser therapy on the rate of orthodontic tooth movement. Orthod Craniofac Res 9(1):38–43PubMed Limpanichkul W, Godfrey K, Srisuk N et al (2006) Effects of low-level laser therapy on the rate of orthodontic tooth movement. Orthod Craniofac Res 9(1):38–43PubMed
34.
Zurück zum Zitat Mistry D, Dalci O, Papageorgiou SN et al (2020) The effects of a clinically feasible application of low-level laser therapy on the rate of orthodontic tooth movement: a triple-blind, split-mouth, randomized controlled trial. Am J Orthod Dentofac Orthop 157(4):444–453 Mistry D, Dalci O, Papageorgiou SN et al (2020) The effects of a clinically feasible application of low-level laser therapy on the rate of orthodontic tooth movement: a triple-blind, split-mouth, randomized controlled trial. Am J Orthod Dentofac Orthop 157(4):444–453
35.
Zurück zum Zitat Dudic A, Giannopoulou C, Kiliaridis S (2013) Factors related to the rate of orthodontically induced tooth movement. Am J Orthod Dentofac Orthop 143(5):616–621 Dudic A, Giannopoulou C, Kiliaridis S (2013) Factors related to the rate of orthodontically induced tooth movement. Am J Orthod Dentofac Orthop 143(5):616–621
36.
Zurück zum Zitat Deguchi T, Takano-Yamamoto T, Yabuuchi T et al (2008) Histomorphometric evaluation of alveolar bone turnover between the maxilla and the mandible during experimental tooth movement in dogs. Am J Orthod Dentofac Orthop 133(6):889–897 Deguchi T, Takano-Yamamoto T, Yabuuchi T et al (2008) Histomorphometric evaluation of alveolar bone turnover between the maxilla and the mandible during experimental tooth movement in dogs. Am J Orthod Dentofac Orthop 133(6):889–897
37.
Zurück zum Zitat Kircelli BH, Pektaṣ ZÖ, Kircelli C (2006) Maxillary molar distalization with a bone-anchored pendulum appliance. Angle Orthod 76(4):650–659PubMed Kircelli BH, Pektaṣ ZÖ, Kircelli C (2006) Maxillary molar distalization with a bone-anchored pendulum appliance. Angle Orthod 76(4):650–659PubMed
38.
Zurück zum Zitat Keles A, Erverdi N, Sezen S (2003) Bodily distalization of molars with absolute anchorage. Angle Orthod 73(4):471–482PubMed Keles A, Erverdi N, Sezen S (2003) Bodily distalization of molars with absolute anchorage. Angle Orthod 73(4):471–482PubMed
39.
Zurück zum Zitat Escobar SA, Tellez PA, Moncada CA et al (2007) Distalization of maxillary molars with the bone-supported pendulum: a clinical study. Am J Orthod Dentofac Orthop 131(4):545–549 Escobar SA, Tellez PA, Moncada CA et al (2007) Distalization of maxillary molars with the bone-supported pendulum: a clinical study. Am J Orthod Dentofac Orthop 131(4):545–549
40.
Zurück zum Zitat Kinzinger GSM, Gülden N, Yildizhan F et al (2009) Efficiency of a skeletonized distal jet appliance supported by miniscrew anchorage for noncompliance maxillary molar distalization. Am J Orthod Dentofac Orthop 136(4):578–586 Kinzinger GSM, Gülden N, Yildizhan F et al (2009) Efficiency of a skeletonized distal jet appliance supported by miniscrew anchorage for noncompliance maxillary molar distalization. Am J Orthod Dentofac Orthop 136(4):578–586
41.
Zurück zum Zitat Nienkemper M, Wilmes B, Pauls A et al (2014) Treatment efficiency of mini-implant-borne distalization depending on age and second-molar eruption. J Orofacial Orthopedics/Fortschritte der Kieferorthopädie 75:118–132 Nienkemper M, Wilmes B, Pauls A et al (2014) Treatment efficiency of mini-implant-borne distalization depending on age and second-molar eruption. J Orofacial Orthopedics/Fortschritte der Kieferorthopädie 75:118–132
Metadaten
Titel
Effect of low-level laser therapy on orthodontic tooth movement during miniscrew-supported maxillary molar distalization in humans: a single-blind, randomized controlled clinical trial
verfasst von
Beren Özsoy
Kemal Güldüren
Beste Kamiloğlu
Publikationsdatum
01.12.2023
Verlag
Springer London
Erschienen in
Lasers in Medical Science / Ausgabe 1/2023
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-023-03736-y

Weitere Artikel der Ausgabe 1/2023

Lasers in Medical Science 1/2023 Zur Ausgabe